Most Home Runs in One Season—45 or More
Updated February 21, 2017 | Factmonster Staff 
| HR | Player/Team | Year |
|---|---|---|
| 73 | Barry Bonds, San Francisco (N.L.) | 2001 |
| 70 | Mark McGwire, St. Louis (N.L.) | 1998 |
| 66 | Sammy Sosa, Chicago (N.L.) | 1998 |
| 65 | Mark McGwire, St. Louis (N.L.) | 1999 |
| 64 | Sammy Sosa, Chicago (N.L.) | 2001 |
| 63 | Sammy Sosa, Chicago (N.L.) | 1999 |
| 61 | Roger Maris, New York (A.L.) | 1961 |
| 60 | Babe Ruth, New York (A.L.) | 1927 |
| 59 | Babe Ruth, New York (A.L.) | 1921 |
| 58 | Jimmie Foxx, Philadelphia (A.L.) | 1932 |
| 58 | Hank Greenberg, Detroit (A.L.) | 1938 |
| 58 | Mark McGwire, Oakland (A.L.), St. Louis (N.L.) | 1997 |
| 58 | Ryan Howard, Philadelphia (N.L.) | 2006 |
| 57 | Luis Gonzalez. Arizona (N.L.) | 2001 |
| 57 | Alex Rodriguez, Texas (A.L.) | 2002 |
| 56 | Hack Wilson, Chicago (N.L.) | 1930 |
| 56 | Ken Griffey, Jr., Seattle (A.L.) | 1997 |
| 56 | Ken Griffey, Jr., Seattle (A.L.) | 1998 |
| 54 | Babe Ruth, New York (A.L.) | 1920 |
| 54 | Babe Ruth, New York (A.L.) | 1928 |
| 54 | Ralph Kiner, Pittsburgh (N.L.) | 1949 |
| 54 | Mickey Mantle, New York (A.L.) | 1961 |
| 54 | David Ortiz, Boston (A.L.) | 2006 |
| 52 | Mickey Mantle, New York (A.L.) | 1956 |
| 52 | Willie Mays, San Francisco (N.L.) | 1965 |
| 52 | George Foster, Cincinnati (N.L.) | 1977 |
| 52 | Mark McGwire, Oakland (A.L.) | 1996 |
| 52 | Alex Rodriguez, Texas (A.L.) | 2001 |
| 52 | Jim Thome, Cleveland (A.L.) | 2002 |
| 51 | Ralph Kiner, Pittsburgh (N.L.) | 1947 |
| 51 | John Mize, New York (N.L.) | 1947 |
| 51 | Willie Mays, New York (N.L.) | 1955 |
| 51 | Cecil Fielder (A.L.) | 1990 |
| 51 | Andruw Jones, Atlanta (N.L.) | 2005 |
| 50 | Jimmie Foxx, Boston (A.L.) | 1938 |
| 50 | Albert Belle, Cleveland (A.L.) | 1995 |
| 50 | Brady Anderson, Baltimore (A.L.) | 1996 |
| 50 | Sammy Sosa, Chicago (N.L.) | 2000 |
| 50 | Greg Vaughn, San Diego (N.L.) | 1998 |
| 49 | Babe Ruth, New York (A.L.) | 1930 |
| 49 | Lou Gehrig, New York (A.L.) | 1934 |
| 49 | Lou Gehrig, New York (A.L.) | 1936 |
| 49 | Ted Kluszewski, Cincinnati (N.L.) | 1954 |
| 49 | Willie Mays, San Francisco (N.L.) | 1962 |
| 49 | Harmon Killebrew, Minnesota (A.L.) | 1964 |
| 49 | Frank Robinson, Baltimore (A.L.) | 1966 |
| 49 | Harmon Killebrew, Minnesota (A.L.) | 1969 |
| 49 | Mark McGwire, Oakland (A.L.) | 1987 |
| 49 | Andre Dawson, Chicago (N.L.) | 1987 |
| 49 | Ken Griffey, Jr., Seattle (A.L.) | 1996 |
| 49 | Larry Walker, Colorado (N.L.) | 1997 |
| 49 | Albert Belle, Chicago (A.L.) | 1998 |
| 49 | Barry Bonds, San Francisco (N.L.) | 2000 |
| 49 | Shawn Green, Los Angeles (N.L.) | 2001 |
| 49 | Todd Helton, Colorado (N.L.) | 2001 |
| 49 | Jim Thome, Cleveland (A.L.) | 2001 |
| 49 | Sammy Sosa, Chicago (N.L.) | 2002 |
| 49 | Albert Pujols, St. Louis (N.L.) | 2006 |
| 48 | Jimmie Foxx, Philadelphia (A.L.) | 1933 |
| 48 | Harmon Killebrew, Minnesota (A.L.) | 1962 |
| 48 | Frank Howard, Washington (A.L.) | 1969 |
| 48 | Willie Stargell, Pittsburgh (N.L.) | 1971 |
| 48 | Dave Kingman, Chicago (N.L.) | 1979 |
| 48 | Mike Schmidt, Philadelphia (N.L.) | 1980 |
| 48 | Albert Belle, Cleveland (A.L.) | 1996 |
| 48 | Ken Griffey, Jr., Seattle (A.L.) | 1999 |
| 48 | Adrian Beltre, Los Angeles (N.L.) | 2004 |
| 48 | Alex Rodriguez, New York (A.L.) | 2005 |
| 47 | Babe Ruth, New York (A.L.) | 1926 |
| 47 | Ralph Kiner, Pittsburgh (N.L.) | 1950 |
| 47 | Ed Mathews, Milwaukee (N.L.) | 1953 |
| 47 | Ernie Banks, Chicago (N.L.) | 1958 |
| 47 | Willie Mays, San Francisco (N.L.) | 1964 |
| 47 | Hank Aaron, Atlanta (N.L.) | 1971 |
| 47 | Reggie Jackson, Oakland (A.L.) | 1969 |
| 47 | George Bell, Toronto (A.L.) | 1987 |
| 47 | Kevin Mitchell, San Francisco (N.L.) | 1989 |
| 47 | Andres Galarraga, Colorado (N.L.) | 1996 |
| 47 | Juan Gonzalez, Texas (A.L.) | 1996 |
| 47 | Rafael Palmeiro, Texas (A.L.) | 1999 |
| 47 | Jeff Bagwell, Houston (N.L.) | 2000 |
| 47 | Troy Glaus, Anaheim (A.L.) | 2000 |
| 47 | Rafael Palmeiro, Texas (A.L.) | 2001 |
| 47 | Alex Rodriguez, Texas (A.L.) | 2003 |
| 47 | Jim Thome, Philadelphia (N.L.) | 2003 |
| 47 | Albert Pujols, St. Louis (N.L.) | 2004 |
| 47 | David Ortiz, Boston (A.L.) | 2005 |
| 46 | Babe Ruth, New York (A.L.) | 1924 |
| 46 | Babe Ruth, New York, (A.L.) | 1929 |
| 46 | Babe Ruth, New York (A.L.) | 1931 |
| 46 | Lou Gehrig, New York (A.L.) | 1931 |
| 46 | Joe DiMaggio, New York (A.L.) | 1937 |
| 46 | Ed Mathews, Milwaukee (N.L.) | 1959 |
| 46 | Orlando Cepeda, San Francisco (N.L.) | 1961 |
| 46 | Jim Rice, Boston (A.L.) | 1978 |
| 46 | Juan Gonzalez, Texas (A.L.) | 1993 |
| 46 | Barry Bonds, San Francisco (N.L.) | 1993 |
| 46 | Jose Canseco, Toronto (A.L.) | 1998 |
| 46 | Vinnie Castilla, Colorado (N.L.) | 1998 |
| 46 | Barry Bonds, San Francisco (N.L.) | 2002 |
| 46 | Adam Dunn, Cincinnati (N.L.) | 2004 |
| 46 | Derrek Lee, Chicago (N.L.) | 2005 |
| 46 | Alfonso Soriano, Washington (N.L.) | 2006 |
| 45 | Ernie Banks, Chicago (N.L.) | 1959 |
| 45 | Harmon Killebrew, Minnesota (A.L.) | 1963 |
| 45 | Willie McCovey, San Francisco (N.L.) | 1969 |
| 45 | Johnny Bench, Cincinnati (N.L.) | 1970 |
| 45 | Gorman Thomas, Milwaukee (A.L.) | 1979 |
| 45 | Hank Aaron, Milwaukee (N.L.) | 1962 |
| 45 | Ken Griffey, Jr., Seattle (A.L.) | 1993 |
| 45 | Juan Gonzalez, Texas (A.L.) | 1998 |
| 45 | Manny Ramirez, Cleveland (A.L.) | 1998 |
| 45 | Chipper Jones, Atlanta (N.L.) | 1999 |
| 45 | Greg Vaughn, Cincinnati (N.L.) | 1999 |
| 45 | Barry Bonds, San Francisco (N.L.) | 2003 |
| 45 | Richie Sexson, Milwaukee (N.L.) | 2003 |
| 45 | Barry Bonds, San Francisco (N.L.) | 2004 |
| 45 | Manny Ramirez, Boston (A.L.) | 2005 |
| 45 | Lance Berkman, Houston (N.L.) | 2006 |
